Explainable machine learning revealing the impact of mental and physical health on arthritis - Takeaways - MDSpire

Explainable machine learning revealing the impact of mental and physical health on arthritis

  • By

  • Md. Atik Shams

  • Sumaiya Fatema

  • D M Hasibul Islam

  • Anindita Datta

  • David Eisenberg

  • Danastan Tasaouf Mridula

  • Junnatul Mawa

  • Asma Sultana

  • Nafiya Ahmed

  • Monowarul Islam

  • Tanmoy Sarkar Pias

  • July 8, 2026

  • 0 min

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  • 1

    The study developed a machine learning framework for predicting arthritis risk using four national datasets.

  • 2

    A stacked ensemble model with GAN imputation and random undersampling achieved the highest AUROC of 0.8007.

  • 3

    SHAP analysis identified age, walking difficulty, BMI, and parental separation as significant predictors of arthritis.

  • 4

    The research highlights the interplay between mental and physical health in the context of arthritis risk.

  • 5

    This study addresses limitations in previous research by employing advanced machine learning techniques and multiple datasets.

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