The Impact of the Microbiome on Gynecological Cancers: Consequences for Diagnosis and Therapeutic Approaches

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Gynecological cancers significantly contribute to global health burdens, accounting for 15.25% of new cancer cases in women in 2022.
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The human microbiome plays a crucial role in the pathogenesis of gynecological cancers, influencing carcinogenesis through microbial dysbiosis.
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Dysbiosis, characterized by reduced Lactobacillus and increased anaerobic organisms, is linked to chronic inflammation and immune modulation.
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Microbial signatures are being explored as non-invasive biomarkers for early diagnosis and monitoring of gynecological cancers.
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Emerging microbiome-based therapies, such as probiotics and microbiota transplantation, show promise as adjunct treatments in gynecological oncology.

Frontiers In Immunology

by Precious Adeoye Oyedokun, Bobola Timothy Oyeleke, Onigbinde Oluwanisola Akanji, Abraham Ololade Oyelaran, Kehinde Philip O, Grace Bosede Akanbi, Philip Olagbede Oyedokun, Marvelous Dasola Oyedokun, Chikezie Chinelo Naomi, Oyeniran Oluwatosin Imoleayo, Roland Eghoghosoa Akhigbe
April 23, 2026

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