Bariatric Surgery and Risk of End-Stage Liver Disease in a Four-Country Cohort Study - Takeaways - MDSpire

Bariatric Surgery and Risk of End-Stage Liver Disease in a Four-Country Cohort Study

  • By

  • Dag Holmberg

  • Giola Santoni

  • My von Euler-Chelpin

  • Joonas H. Kauppila

  • Eivind Ness-Jensen

  • Jesper Lagergren

  • April 12, 2025

  • 0 min

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  • 1

    Metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in 25% of adults and 80-90% of those with morbid obesity.

  • 2

    Bariatric surgery leads to significant weight loss and histologic improvements in MASLD, but may also increase substance addiction risks.

  • 3

    This study investigates the long-term impact of bariatric surgery on the risk of developing end-stage liver disease in a Nordic cohort.

  • 4

    The cohort included adults with obesity diagnoses from Denmark, Finland, Norway, and Sweden, with data spanning over three decades.

  • 5

    End-stage liver disease outcomes were assessed using national registries, focusing on diagnoses like cirrhosis and liver failure.

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