Population characteristics of children with short stature and construction of a predictive model for growth hormone treatment efficacy

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The study analyzed 400 children diagnosed with short stature, categorizing them into growth hormone, nutritional support, and untreated groups.
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The growth hormone intervention group demonstrated significantly higher annualized growth velocity compared to the nutritional support group (p < 0.05).
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Duration of growth hormone therapy was identified as the independent predictor of treatment efficacy, with an odds ratio of 4.45 (p = 0.006).
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A nomogram model was developed using six variables and showed good discrimination and calibration for predicting growth hormone treatment efficacy.
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The predictive model is intended for intra-treatment efficacy evaluation, aiding clinicians in individualized patient management and follow-up.

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