Cytokine Dynamics During Acute Infections of Dengue, Zika, Chikungunya, and Mayaro Viruses in Northern Peru - Takeaways - MDSpire
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Cytokine Dynamics During Acute Infections of Dengue, Zika, Chikungunya, and Mayaro Viruses in Northern Peru

  • By

  • Juana del Valle-Mendoza

  • Hugh Watson

  • Yordi Tarazona-Castro

  • Wilmer Silva-Caso

  • Ronald Aquino-Ortega

  • Hugo Carrillo-Ng

  • Jorge Bazan-Mayra

  • Victor Zavaleta-Gavidia

  • Miguel Angel Aguilar-Luis

  • January 17, 2026

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  • 1

    Acute febrile illness (AFI) in Peru is significantly impacted by arboviruses like Dengue, Zika, Chikungunya, and Mayaro, complicating clinical diagnosis.

  • 2

    Cytokines play a crucial role in arboviral pathogenesis and may serve as diagnostic and prognostic biomarkers for infections.

  • 3

    Distinct cytokine profiles are associated with each arbovirus, with specific markers linked to disease severity and immune responses.

  • 4

    The study analyzed cytokine levels in patients with confirmed arboviral infections to improve diagnostic accuracy and clinical outcomes.

  • 5

    Cajamarca, Peru, was the study location, where diverse etiological agents of AFI, including arboviruses, were previously reported.

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