Global burden and temporal trends of kidney cancer among children from 1990 to 2021: an analysis with projections to 2036 - Takeaways - MDSpire

Global burden and temporal trends of kidney cancer among children from 1990 to 2021: an analysis with projections to 2036

  • By

  • Kai Liu

  • Changlin Yang

  • Feng Chen

  • Xuhua Qiao

  • Yujie Geng

  • Chundong Ji

  • July 9, 2026

  • 0 min

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  • 1

    Childhood kidney cancer (KC) is the third most prevalent pediatric solid malignancy, accounting for 3.2% to 11.1% of pediatric cancers globally.

  • 2

    In 2021, there were 9,576 incident cases, 3,063 deaths, and 268,049 disability-adjusted life years (DALYs) due to childhood KC worldwide.

  • 3

    From 1990 to 2021, the global burden of childhood KC declined, with a steeper decline observed from 2018 to 2021.

  • 4

    The burden of childhood KC is concentrated among children aged 0–4 years, with higher incidence, mortality, and DALY rates compared to older age groups.

  • 5

    Health inequities in childhood KC are evident, with mortality and DALYs disproportionately concentrated in lower-SDI countries, and these disparities have widened over time.

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