Hybrid Management of Subclavian-Axillary Artery Aneurysms in Loeys-Dietz Syndrome After Prior Aortic Arch Repair: Technical Note - Takeaways - MDSpire

Hybrid Management of Subclavian-Axillary Artery Aneurysms in Loeys-Dietz Syndrome After Prior Aortic Arch Repair: Technical Note

  • By

  • George Apostolidis

  • Tilo Kölbel

  • Petroula Nana

  • Jose I. Torrealba

  • Meike Rybczynski

  • Giuseppe Panuccio

  • June 30, 2026

  • 0 min

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  • 1

    Syndromic hereditary thoracic aortic diseases are associated with aneurysms and dissections in various vascular beds, particularly in Loeys-Dietz syndrome patients.

  • 2

    Open surgical repair is standard for managing sHTAD, but high morbidity has led to the exploration of less invasive endovascular and hybrid strategies.

  • 3

    A hybrid technique combining endovascular stent-graft implantation with open distal anastomosis was used to manage subclavian-axillary artery aneurysms in two LDS cases.

  • 4

    In case 1, a two-staged approach prioritized aortic arch repair followed by a hybrid repair for a right subclavian artery aneurysm.

  • 5

    In case 2, a hybrid approach was utilized for an extensive left axillary artery aneurysm after multiple previous surgeries and replaced proximal landing zones.

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