Sex differences in iron stores and associations of body iron with cardiovascular risk factors in the middle-aged general population - Takeaways - MDSpire

Sex differences in iron stores and associations of body iron with cardiovascular risk factors in the middle-aged general population

  • By

  • Wei Li

  • Mats Fredriksson

  • Dženeta Nezirević Dernroth

  • Hevi Mahmod

  • Xiao-Mei Mai

  • Carl Johan Östgren

  • Xi-Ming Yuan

  • May 15, 2026

  • 0 min

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  • 1

    Men exhibited higher total body iron and ferritin levels compared to both premenopausal and postmenopausal women.

  • 2

    Men showed a more adverse cardiovascular risk profile, including higher BMI, hypertension, and diabetes prevalence than women.

  • 3

    The prevalence of hyperferritinemia was significantly higher in men (21.6%) compared to women (12.0%).

  • 4

    In both sexes, ferritin levels were associated with BMI, alcohol consumption, LDL cholesterol, and triglycerides.

  • 5

    Age and hypertension were significantly associated with ferritin levels in women, but not in men, highlighting sex-specific differences.

Original Source(s)

Sex differences in iron stores and associations of body iron with cardiovascular risk factors in the middle-aged general population

  • by Wei Li, Mats Fredriksson, Dženeta Nezirević Dernroth, Hevi Mahmod, Xiao-Mei Mai, Carl Johan Östgren, Xi-Ming Yuan

  • May 15, 2026

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