Multifactorial stratified analysis of two novel metabolism-related indices for predicting stroke in mild cognitive impairment - Takeaways - MDSpire

Multifactorial stratified analysis of two novel metabolism-related indices for predicting stroke in mild cognitive impairment

  • By

  • Boyuan Qiu

  • Hongliang Tang

  • Liangyuan Tan

  • Peng Yang

  • Wenhui Wang

  • Peipei Yang

  • Kailong Wang

  • July 13, 2026

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  • 1

    The study evaluated the predictive value of the C-reactive protein-triglyceride glucose index (CTI) and Body Roundness Index (BRI) for stroke in mild cognitive impairment (MCI) patients.

  • 2

    Data from the China Health and Retirement Longitudinal Study (CHARLS) included 907 participants, with 81 experiencing a stroke during the follow-up period.

  • 3

    Each one-unit increase in CTI was linked to a 34% higher stroke risk among MCI patients, while BRI showed no significant correlation with stroke occurrence.

  • 4

    CTI's predictive performance remained consistent across different demographic groups, with optimal cutoff values identified ranging from 8.20 to 9.28.

  • 5

    The association between CTI and stroke risk was more pronounced in females, married individuals, and patients under 65 years of age.

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