Association between heavy metals, essential trace elements in follicular fluid and diminished ovarian reserve: a hospital-based case-control study - Takeaways - MDSpire

Association between heavy metals, essential trace elements in follicular fluid and diminished ovarian reserve: a hospital-based case-control study

  • By

  • Xin-chen Huang

  • Ming-li Sun

  • Yi-qin Chen

  • Xin-lan Zhang

  • Xin-yao Song

  • Wen-xiang Wang

  • Yan Sun

  • July 2, 2026

  • 0 min

Share

  • 1

    The study investigates the association between heavy metals and essential trace elements in follicular fluid and diminished ovarian reserve (DOR).

  • 2

    Higher concentrations of arsenic, strontium, and calcium were found in the follicular fluid of women with DOR compared to controls.

  • 3

    Logistic regression indicated that arsenic and strontium were associated with increased odds of DOR, while copper, vanadium, and zinc were linked to lower odds.

  • 4

    The weighted quantile sum regression identified strontium, arsenic, and calcium as primary contributors to the mixture effect on DOR.

  • 5

    Maintaining trace element homeostasis may be critical for preserving ovarian reserve, as indicated by the study's findings.

Original Source(s)

Association between heavy metals, essential trace elements in follicular fluid and diminished ovarian reserve: a hospital-based case-control study

  • by Xin-chen Huang, Ming-li Sun, Yi-qin Chen, Xin-lan Zhang, Xin-yao Song, Wen-xiang Wang, Yan Sun

  • July 2, 2026

Related Content

Pregnancy-Related Clinical Codes in Unlikely Populations in Primary Care

Identification of key vaginal microbial signatures and immune remodeling associated with HR-HPV clearance following Kushen Gel treatment: a longitudinal analysis

Roswell Park Introduces Gyn-Onc Connect Line for Consultation

To better service community practitioners, Roswell Park Comprehensive Cancer Center is proud to introduce Gyn-Onc Connect, a dedicated phone number to access Roswell Park’s gynecologic oncology team.

  • by

  • June 29, 2026

  • 1 min