Analysis of risk factors for hemorrhagic transformation after mechanical thrombectomy in acute anterior circulation large vessel occlusion stroke and construction of a nomogram prediction model - Takeaways - MDSpire

Analysis of risk factors for hemorrhagic transformation after mechanical thrombectomy in acute anterior circulation large vessel occlusion stroke and construction of a nomogram prediction model

  • By

  • Mujie Yao

  • Keqi Lei

  • Yue Wan

  • May 29, 2026

  • 0 min

Share

  • 1

    This study identified six independent risk factors for hemorrhagic transformation (HT) after mechanical thrombectomy in acute anterior circulation large vessel occlusion stroke.

  • 2

    The identified risk factors include history of alcohol consumption, leukoencephalopathy, elevated blood glucose-to-lymphocyte ratio, D-dimer, venous blood glucose, and reduced mean platelet volume.

  • 3

    A predictive nomogram was developed, demonstrating good discrimination with an AUC of 0.880, sensitivity of 0.933, and specificity of 0.696.

  • 4

    Calibration curve analysis indicated a good model fit for the nomogram, with a χ2 value of 9.059 and a p-value of 0.337.

  • 5

    The study emphasizes the importance of identifying HT risk factors to enhance functional recovery and long-term prognosis in stroke patients.

Original Source(s)

Related Content