Performance and safety of the Colovac 2 colorectal anastomotic protection device: the SafeHeal SAFE-2023 study - Takeaways - MDSpire

Performance and safety of the Colovac 2 colorectal anastomotic protection device: the SafeHeal SAFE-2023 study

  • By

  • Lefevre, Jeremie H.

  • Karachun, Aleksei

  • Sametdinov, Narkhodzha

  • Raximov, Oqiljon

  • Rustamov, Akmalkhuja

  • Adilkhodjaev, Askar

  • Yunusov, Seydamet

  • Mirzagolib, Tillyashaikhov

  • Sylla, Patricia

  • March 5, 2026

  • 0 min

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  • 1

    The Colovac 2 device aims to protect colorectal anastomosis and reduce complications associated with temporary diverting ostomies.

  • 2

    Colovac 2 is designed for internal protection during the early postoperative period, allowing for better recovery without the need for ostomies.

  • 3

    The SAFE-2023 study evaluated the performance, safety, and usability of Colovac 2 in patients undergoing low anterior resection.

  • 4

    Primary endpoints included assessing clinically significant migration rates and ostomy avoidance rates by Day 10 post-procedure.

  • 5

    The study was conducted in accordance with ethical standards and included experienced colorectal surgeons at two centers in Uzbekistan.

Original Source(s)

Performance and safety of the Colovac 2 colorectal anastomotic protection device: the SafeHeal SAFE-2023 study

  • by Lefevre, Jeremie H., Karachun, Aleksei, Sametdinov, Narkhodzha, Raximov, Oqiljon, Rustamov, Akmalkhuja, Adilkhodjaev, Askar, Yunusov, Seydamet, Mirzagolib, Tillyashaikhov, Sylla, Patricia

  • March 5, 2026

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