The histological representativeness of glioblastoma tissue samples - Takeaways - MDSpire

The histological representativeness of glioblastoma tissue samples

  • By

  • Vilde Elisabeth Mikkelsen

  • Ole Solheim

  • Øyvind Salvesen

  • Sverre Helge Torp

  • October 21, 2020

  • 0 min

Share

  • 1

    Glioblastomas are the most common and malignant primary brain tumors in adults, with a median survival of 10–14 months.

  • 2

    Histological heterogeneity in GBMs increases the risk of non-representative tumor samples, impacting diagnostic accuracy.

  • 3

    The WHO classification of GBMs includes histological grading based on features like atypia, mitotic activity, and necrosis.

  • 4

    Tissue amount on HE slides correlates with the presence of histopathological features and may affect GBM diagnosis.

  • 5

    Comprehensive molecular analyses, while promising, are not widely available, highlighting limitations in glioma diagnostics.

Original Source(s)

The histological representativeness of glioblastoma tissue samples

  • by Vilde Elisabeth Mikkelsen, Ole Solheim, Øyvind Salvesen, Sverre Helge Torp

  • October 21, 2020

Related Content

Ablative stereotactic MR-guided radiotherapy for >10 cm solid pseudopapillary tumor of the pancreas with liver oligometastases: a case report and literature review

Case Report: Long-term survival in advanced PD-L1-high squamous cell lung cancer following severe immune-related cardiotoxicity

First Patient Treated with Proton Therapy at Lynn Cancer Institute

The Eugene M. & Christine E. Lynn Cancer Institute at Boca Raton Regional Hospital, part of Baptist Health, reached an important milestone in the advancement of cancer care with the successful treatment of its first patient utilizing proton therapy, according to physicians at both the Institute and the hospital.

  • by

  • May 15, 2026

  • 5 min