Editorial: Natural products in bone health and disease: mechanisms, therapeutics, and clinical potential - Takeaways - MDSpire
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Editorial: The Role of Natural Compounds in Bone Health and Disorders: Mechanisms, Treatment Options, and Clinical Implications

  • By

  • Kok-Yong Chin

  • Kok-Lun Pang

  • September 8, 2026

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  • 1

    Osteoporosis significantly impacts global health, with low bone mineral density causing over 219,000 deaths and millions of disability-adjusted life years.

  • 2

    Natural compounds, including herbal products and vitamins, show potential in treating chronic skeletal diseases through multi-target mechanisms.

  • 3

    Vitamin K2 supplementation has been shown to improve bone health by increasing osteocalcin levels and reducing markers of bone resorption.

  • 4

    Tocotrienols may protect osteocytes from oxidative stress, promoting bone quality and strength through various cellular pathways.

  • 5

    A study found thyroid hormone levels correlate with vertebral fracture risk, suggesting their potential role in osteoporosis management.

Original Source(s)

Editorial: Natural products in bone health and disease: mechanisms, therapeutics, and clinical potential

  • by Kok-Yong Chin, Kok-Lun Pang

  • September 8, 2026

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