The Cortical Asymmetry Index for subtyping dementia patients - Takeaways - MDSpire

The Cortical Asymmetry Index for subtyping dementia patients

  • By

  • Agnès Pérez-Millan

  • Uma Maria Lal-Trehan Estrada

  • Neus Falgàs

  • Núria Guillén

  • Sergi Borrego-Écija

  • Jordi Juncà-Parella

  • Beatriz Bosch

  • Adrià Tort-Merino

  • Jordi Sarto

  • Josep Maria Augé

  • Anna Antonell

  • Núria Bargalló

  • Raquel Ruiz-García

  • Laura Naranjo

  • Mircea Balasa

  • Albert Lladó

  • Roser Sala-Llonch

  • Raquel Sánchez-Valle

  • February 11, 2025

  • 0 min

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  • 1

    Frontotemporal dementia (FTD) is often misdiagnosed as Alzheimer's disease (AD), particularly in younger patients.

  • 2

    Cortical asymmetry may serve as a diagnostic tool to differentiate between FTD and AD, as well as among FTD subtypes.

  • 3

    The study defined the Cortical Asymmetry Index (CAI) using cortical thickness measures to assess brain asymmetry.

  • 4

    Participants included 554 individuals, with 101 diagnosed with FTD, 230 with AD, and 173 healthy controls.

  • 5

    The research aimed to evaluate CAI's correlation with cognitive measures and biomarkers to track dementia progression.

Original Source(s)

The Cortical Asymmetry Index for subtyping dementia patients

  • by Agnès Pérez-Millan, Uma Maria Lal-Trehan Estrada, Neus Falgàs, Núria Guillén, Sergi Borrego-Écija, Jordi Juncà-Parella, Beatriz Bosch, Adrià Tort-Merino, Jordi Sarto, Josep Maria Augé, Anna Antonell, Núria Bargalló, Raquel Ruiz-García, Laura Naranjo, Mircea Balasa, Albert Lladó, Roser Sala-Llonch, Raquel Sánchez-Valle

  • February 11, 2025

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