Which biomarkers predict risk better in women? - Takeaways - MDSpire

Which biomarkers predict risk better in women?

  • By

  • Lale Tokgözoğlu

  • Meral Kayıkçıoğlu

  • October 29, 2025

  • 0 min

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  • 1

    Atherosclerotic cardiovascular disease is the leading cause of mortality among women, yet prevention relies on male-validated algorithms and biomarkers.

  • 2

    Women experience higher lifetime cardiovascular risk post-menopause due to atherogenic dyslipidemia, necessitating sex-specific risk factor recognition.

  • 3

    In a study of 866 high-risk patients, certain lipid biomarkers showed sex-specific predictive value for major cardiovascular events.

  • 4

    The omission of Lp(a) and non-HDL-C in the study limits comprehensive interpretation of lipid-based sex differences in cardiovascular risk.

  • 5

    Current evidence suggests ApoB or non-HDL-C should complement LDL-C for more accurate cardiovascular risk assessment in women.

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