Fibrinogen-to-albumin ratio independently predicts left ventricular aneurysm in STEMI patients: a retrospective cohort study - Takeaways - MDSpire

Fibrinogen-to-albumin ratio independently predicts left ventricular aneurysm in STEMI patients: a retrospective cohort study

  • By

  • Qinshuo Zhao

  • Mengying He

  • Dong Hu

  • Wei Song

  • Xiao Li

  • July 8, 2026

  • 0 min

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  • 1

    The study included 1,245 STEMI patients undergoing primary percutaneous coronary intervention from January 2020 to December 2025.

  • 2

    High fibrinogen-to-albumin ratio (FAR) was independently associated with left ventricular aneurysm (LVA) in the development cohort.

  • 3

    The combined prediction model incorporating FAR, left ventricular ejection fraction, and NT-proBNP showed high discrimination with an AUC of 0.933.

  • 4

    Temporal validation with an independent cohort confirmed the model's performance, achieving an AUC of 0.934 and acceptable calibration.

  • 5

    Elevated FAR is linked to increased LVA risk in STEMI patients, highlighting its potential as a predictive biomarker.

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