Stereotactic Body Radiotherapy (SBRT) of Previously Unirradiated Mucosal Head and Neck Squamous Cell Carcinoma (SCC) - Takeaways - MDSpire

Stereotactic Body Radiotherapy for Untreated Mucosal Squamous Cell Carcinoma of the Head and Neck

  • By

  • Mohammed Aldohan

  • Irene Karam

  • Amir H. Safavi

  • Lee Chin

  • Liying Zhang

  • Ethan Gooanratne

  • Madette Galapin

  • Antoine Eskander

  • Kevin Higgins

  • Danny Enepekides

  • Ian Poon

  • June 29, 2026

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  • 1

    Stereotactic body radiotherapy (SBRT) was evaluated for 74 patients with untreated mucosal squamous cell carcinoma of the head and neck.

  • 2

    Patients selected for SBRT were deemed unsuitable for radical treatment and systemic therapy, highlighting a need for alternative options.

  • 3

    SBRT dosages ranged from 35 to 50 Gy delivered in 5 fractions, aiming for high tumor coverage with minimal toxicity.

  • 4

    Outcomes measured included local failure, regional recurrence, overall survival, and progression-free survival using Kaplan-Meier plots.

  • 5

    Toxicity was assessed according to the Common Terminology Criteria for Adverse Events, version 5.0.

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