The endocrine pathway during whole body vibration modulates the immune system and the osteogenesis in postmenopausal women with osteoporosis - Takeaways - MDSpire

The endocrine pathway during whole body vibration modulates the immune system and the osteogenesis in postmenopausal women with osteoporosis

  • By

  • Vasiliy Pyatin

  • Olga Maslova

  • May 15, 2026

  • 0 min

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  • 1

    Whole-body vibration (WBV) exercise enhances bone mineral density by 1.56% in postmenopausal women with osteoporosis after six months.

  • 2

    The study proposes a brain-immune interaction hypothesis that regulates osteogenesis through an integrative proprioceptive endocrine pathway.

  • 3

    Osteoimmunology explores the relationship between the immune system and bone remodeling, particularly in the context of physical activity.

  • 4

    Changes in peripheral blood lymphocyte subpopulations and serum humoral immunity were observed in participants undergoing WBV.

  • 5

    The findings suggest that WBV may serve as a rehabilitation strategy to improve musculoskeletal function in elderly women with osteoporosis.

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