Atherogenic index of plasma and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus: a retrospective cross-sectional study - Takeaways - MDSpire

Atherogenic index of plasma and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus: a retrospective cross-sectional study

  • By

  • Juan Liao

  • Wenzhao Zhang

  • Liqing Peng

  • Jing Huang

  • Gen Chen

  • Jianqun Yu

  • May 29, 2026

  • 0 min

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  • 1

    The study analyzed the relationship between the Atherogenic Index of Plasma (AIP) and coronary artery stenosis severity in type 2 diabetes mellitus patients.

  • 2

    303 T2DM patients who had not received statin treatment and underwent coronary computed tomography angiography were included in the analysis.

  • 3

    A dose-response trend was observed, with higher AIP quartiles correlating with increased severity of coronary stenosis (P for trend <0.01).

  • 4

    The median AIP was significantly higher in patients with severe stenosis (≥70%) compared to those with non-obstructive disease (0.14 vs. 0.05, P<0.001).

  • 5

    AIP was independently associated with obstructive stenosis (≥50%), with an odds ratio of 3.93, and demonstrated better discriminative ability than traditional lipid markers.

Original Source(s)

Atherogenic index of plasma and the severity of coronary artery stenosis in patients with type 2 diabetes mellitus: a retrospective cross-sectional study

  • by Juan Liao, Wenzhao Zhang, Liqing Peng, Jing Huang, Gen Chen, Jianqun Yu

  • May 29, 2026

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