Muscle and fat composition in patients with newly diagnosed multiple myeloma - Takeaways - MDSpire

Muscle and fat composition in patients with newly diagnosed multiple myeloma

  • By

  • Nadine H. Abdallah

  • Hiroki Nagayama

  • Naoki Takahashi

  • Wilson Gonsalves

  • Amie Fonder

  • Angela Dispenzieri

  • David Dingli

  • Francis K. Buadi

  • Martha Q. Lacy

  • Miriam Hobbs

  • Morie A. Gertz

  • Moritz Binder

  • Prashant Kapoor

  • Rahma Warsame

  • Suzanne R. Hayman

  • Taxiarchis Kourelis

  • Yi L. Hwa

  • Yi Lin

  • Robert A. Kyle

  • S. Vincent Rajkumar

  • Stephen M. Broski

  • Shaji K. Kumar

  • December 12, 2023

  • 0 min

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  • 1

    Multiple myeloma (MM) outcomes vary due to disease-related and host-specific characteristics, including body composition.

  • 2

    Sarcopenia, defined by low skeletal muscle index, is linked to adverse health outcomes in cancer patients, including those with MM.

  • 3

    This study analyzed muscle and fat composition in 341 newly diagnosed MM patients using 18F-FDG PET/CT imaging.

  • 4

    Statistical analysis included Cox proportional hazard models to evaluate the impact of body composition on progression-free and overall survival.

  • 5

    The median follow-up for patients was 5.7 years, with median progression-free survival of 37.9 months and overall survival of 7.7 months.

Original Source(s)

Muscle and fat composition in patients with newly diagnosed multiple myeloma

  • by Nadine H. Abdallah, Hiroki Nagayama, Naoki Takahashi, Wilson Gonsalves, Amie Fonder, Angela Dispenzieri, David Dingli, Francis K. Buadi, Martha Q. Lacy, Miriam Hobbs, Morie A. Gertz, Moritz Binder, Prashant Kapoor, Rahma Warsame, Suzanne R. Hayman, Taxiarchis Kourelis, Yi L. Hwa, Yi Lin, Robert A. Kyle, S. Vincent Rajkumar, Stephen M. Broski, Shaji K. Kumar

  • December 12, 2023

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