Effects of Atrial Fibrillation Screening According to Thyroid Function: Post Hoc Analysis of the Randomized LOOP Study - Takeaways - MDSpire

Effects of Atrial Fibrillation Screening According to Thyroid Function: Post Hoc Analysis of the Randomized LOOP Study

  • By

  • Daniel Camillo Spona

  • Diana My Frodi

  • Lucas Yixi Xing

  • Emilie Katrine Kongebro

  • Ketil Jørgen Haugan

  • Claus Graff

  • Søren Højberg

  • Derk Krieger

  • Axel Brandes

  • Lars Køber

  • Morten S Olesen

  • Andreas Andersen

  • Sofie Hædersdal

  • Ruth Frikke-Schmidt

  • Jesper Hastrup Svendsen

  • Søren Zöga Diederichsen

  • September 4, 2024

  • 0 min

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  • 1

    Subclinical thyroid dysfunction is associated with increased atrial fibrillation (AF) and stroke risk, highlighting the importance of thyroid-stimulating hormone (TSH) levels.

  • 2

    In the LOOP study, AF detection was significantly higher in participants screened with an implantable loop recorder (ILR) compared to usual care.

  • 3

    Screening with ILR resulted in a reduced risk of stroke and cardiovascular death among participants with low TSH levels.

  • 4

    No significant benefits of AF screening were observed in participants with higher TSH levels, indicating a potential threshold effect.

  • 5

    The findings suggest that TSH may help identify individuals who would benefit most from AF screening, warranting further investigation.

Original Source(s)

Effects of Atrial Fibrillation Screening According to Thyroid Function: Post Hoc Analysis of the Randomized LOOP Study

  • by Daniel Camillo Spona, Diana My Frodi, Lucas Yixi Xing, Emilie Katrine Kongebro, Ketil Jørgen Haugan, Claus Graff, Søren Højberg, Derk Krieger, Axel Brandes, Lars Køber, Morten S Olesen, Andreas Andersen, Sofie Hædersdal, Ruth Frikke-Schmidt, Jesper Hastrup Svendsen, Søren Zöga Diederichsen

  • September 4, 2024

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