Levels of vascular endothelial growth factor and filtration surgery outcomes in diabetic patients with acute primary angle closure - Takeaways - MDSpire

Levels of vascular endothelial growth factor and filtration surgery outcomes in diabetic patients with acute primary angle closure

  • By

  • Tianwei Qian

  • Mingshui Fu

  • Hao Zhou

  • Zhihua Zhang

  • Ying Hu

  • July 14, 2026

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  • 1

    The study evaluated aqueous humor VEGF levels in diabetic patients with acute primary angle closure undergoing filtration surgery.

  • 2

    A total of 46 eyes were analyzed, with outcomes categorized into success (34 eyes) and failure (12 eyes) groups.

  • 3

    Higher aqueous humor VEGF levels were significantly associated with surgical failure, with P = 0.0018 and odds ratios indicating increased risk.

  • 4

    The low-VEGF group showed a significantly higher success rate compared to the high-VEGF group, with overall success P = 0.0276.

  • 5

    VEGF levels positively correlated with bleb scores, suggesting a relationship between VEGF concentration and surgical outcomes.

Original Source(s)

Levels of vascular endothelial growth factor and filtration surgery outcomes in diabetic patients with acute primary angle closure

  • by Tianwei Qian, Mingshui Fu, Hao Zhou, Zhihua Zhang, Ying Hu

  • July 14, 2026

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