Persistent Subclinical Inflammation and Long-term Functional and Cognitive Outcomes After Dengue Shock and Septic Shock in Vietnam - Takeaways - MDSpire

Persistent Subclinical Inflammation and Long-term Functional and Cognitive Outcomes After Dengue Shock and Septic Shock in Vietnam

  • By

  • Angela McBride

  • Nguyen Lam Vuong

  • Huynh Thi Le Duyen

  • Phan Vinh Tho

  • Luong Thi Hue Tai

  • Nuyen Thanh Phong

  • Nguyen Thanh Ngoc

  • Lam Minh Yen

  • Nguyen Van Hao

  • Sophie Yacoub

  • Martin J Llewelyn

  • Louise Thwaites

  • October 8, 2025

  • 0 min

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  • 1

    This study is the first to report on functional, cognitive, and inflammatory outcomes after dengue shock and septic shock in Vietnam.

  • 2

    Survivors of dengue shock showed high health-related quality of life scores, while those with septic shock had persistently lower scores.

  • 3

    Cognitive function in dengue shock survivors normalized by three months, but septic shock survivors did not reach normal cognitive levels.

  • 4

    Both dengue and septic shock survivors exhibited elevated inflammatory markers, such as IL-6 and ferritin, at all follow-up points.

  • 5

    The findings highlight the need for further research on persistent inflammation and its clinical significance in post-shock recovery.

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