Added value of systematic biopsy in men with a clinical suspicion of prostate cancer undergoing biparametric MRI-targeted biopsy: multi-institutional external validation study

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Biparametric MRI enhances prostate cancer diagnosis by characterizing lesions and enabling targeted biopsies without contrast agents.
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Systematic biopsy may lead to unnecessary complications and incidental detection of clinically insignificant prostate cancer.
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Omitting systematic biopsy risks missing approximately 16% of clinically significant prostate cancer in biopsy-naive patients.
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A nomogram based on MRI volumetric parameters aims to determine when systematic biopsy is necessary alongside targeted biopsy.
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The study analyzed data from 499 patients across two trials to validate the effectiveness of MRI-targeted biopsy versus systematic biopsy.

World Journal Of Urology

by Ugo Falagario, Ivan Jambor, Pekka Taimen, Kari T. Syvänen, Esa Kähkönen, Harri Merisaari, Ileana Montoya Perez, Juha Knaapila, Aida Steiner, Janne Verho, Ashutosh Tewari, Hannu J. Aronen, Giuseppe Carrieri, Peter J. Boström, Otto Ettala
August 10, 2020

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