Indocyanine green combined with autologous blood and methylene blue for pulmonary nodules localization in 272 cases: a novel localization method - Takeaways - MDSpire

Indocyanine green combined with autologous blood and methylene blue for pulmonary nodules localization in 272 cases: a novel localization method

  • By

  • Quan Du

  • Zijie Wang

  • Jian Chen

  • Hong Chen

  • Yuanrong Tu

  • Min Lin

  • Jianfeng Chen

  • August 11, 2025

  • 0 min

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  • 1

    Lung cancer is the second most common cancer and the leading cause of cancer-related deaths globally, with early-stage surgery significantly improving survival rates.

  • 2

    Indocyanine green (ICG) combined with autologous blood and methylene blue offers a novel and effective method for localizing small pulmonary nodules.

  • 3

    The study involved 272 patients with pulmonary nodules, demonstrating the efficacy of the ICG-based localization technique in preoperative settings.

  • 4

    The localization procedure utilized CT-guided injection of the mixed agent, optimizing dosage to enhance visibility and minimize complications.

  • 5

    Successful localization was assessed using a scoring system, with higher scores indicating better visibility and assistance for surgeons during operations.

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