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1
Myopia prevalence is rising globally, particularly in East and Southeast Asia, with projections suggesting nearly half the population may be myopic by 2050.
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2
Environmental factors, including urbanization and lifestyle changes, are recognized as primary drivers of the increasing myopia prevalence.
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3
High-altitude populations exhibit lower myopia prevalence compared to lowland regions, indicating potential protective environmental influences.
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4
Altitude-related exposures, such as hypobaric hypoxia and enhanced solar radiation, may influence ocular growth through biological and behavioral pathways.
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5
Future research should focus on integrating environmental monitoring and longitudinal studies to better understand altitude's impact on refractive development.