Spatial altitude factors on the association with myopia: a narrative review - Takeaways - MDSpire

The Impact of Elevation on Myopia: A Comprehensive Review

  • By

  • Jian Huang

  • Xiaoqiong Li

  • Shunming Liu

  • Li Qi

  • Lei Liu

  • July 20, 2026

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  • 1

    Myopia prevalence is rising globally, particularly in East and Southeast Asia, with projections suggesting nearly half the population may be myopic by 2050.

  • 2

    Environmental factors, including urbanization and lifestyle changes, are recognized as primary drivers of the increasing myopia prevalence.

  • 3

    High-altitude populations exhibit lower myopia prevalence compared to lowland regions, indicating potential protective environmental influences.

  • 4

    Altitude-related exposures, such as hypobaric hypoxia and enhanced solar radiation, may influence ocular growth through biological and behavioral pathways.

  • 5

    Future research should focus on integrating environmental monitoring and longitudinal studies to better understand altitude's impact on refractive development.

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