Sigmoid colonic tuberculosis presenting as a colovesical fistula mimicking colorectal malignancy: a case report - Takeaways - MDSpire

Sigmoid colonic tuberculosis presenting as a colovesical fistula mimicking colorectal malignancy: a case report

  • By

  • Lingfeng Zhong

  • Kun Xia

  • Yanyun Fan

  • June 8, 2026

  • 0 min

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  • 1

    Isolated sigmoid tuberculosis is rare and can mimic colorectal cancer or Crohn's disease due to similar imaging findings.

  • 2

    A 73-year-old man presented with diarrhea, fever, and urinary symptoms, leading to elevated inflammatory markers and anemia.

  • 3

    Initial histopathology showed nonspecific inflammation without granulomas, complicating the diagnosis of intestinal tuberculosis.

  • 4

    Integration of imaging, immunological testing, and molecular diagnostics was crucial for confirming the diagnosis of intestinal tuberculosis.

  • 5

    Standard anti-tuberculosis therapy resulted in rapid clinical improvement and resolution of the colovesical fistula.

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