Glucometabolic Control and Anti-Transglutaminase Antibodies at Celiac Disease Onset in Type 1 Diabetes Youth - Takeaways - MDSpire

Glucometabolic Control and Anti-Transglutaminase Antibodies at Celiac Disease Onset in Type 1 Diabetes Youth

  • By

  • Francesca Di Candia

  • Francesco Maria Rosanio

  • Roberto Franceschi

  • Alessandro Fierro

  • Riccardo Bonfanti

  • Francesca Cardella

  • Valentino Cherubini

  • Giuseppe D’Annunzio

  • Barbara Felappi

  • Dario Iafusco

  • Brunella Iovane

  • Claudio Maffeis

  • Giulio Maltoni

  • Francesca Olivieri

  • Gabriele Olivieri

  • Barbara Piccini

  • Elvira Piccinno

  • Barbara Predieri

  • Ivana Rabbone

  • Maria Rossella Ricciardi

  • Giuseppina Salzano

  • Riccardo Schiaffini

  • Gianluca Tornese

  • Angela Zanfardino

  • Marco Marigliano

  • Riccardo Troncone

  • Riccardo Pertile

  • Luigi Greco

  • Renata Auricchio

  • Enza Mozzillo

  • ISPED Diabetes Study Group Collaborators

  • Francesco Gallo

  • Caterina Grosso

  • Carlo Ripoli

  • Fiorella De Berardinis

  • Susanna Coccoli

  • Valentina Tiberi

  • Sonia Toni

  • Maurizio Delvecchio

  • Rosanna Roppolo

  • Fortunato Lombardo

  • Stefano Passanisi

  • Bruno Bombaci

  • Alberto Casertano

  • Nicola Minuto

  • Marta Bassi

  • Evelina Maines

  • Silvia Savastio

  • Elena Inzaghi

  • Andrea Rigamonti

  • Giulio Frontino

  • Patrizia Bruzzi

  • Claudia Piona

  • November 4, 2025

  • 0 min

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  • 1

    The study correlates anti-TTG IgA titer and HbA1c levels at celiac disease diagnosis in youth with type 1 diabetes.

  • 2

    Higher HbA1c levels are associated with increased fold-anti-TTG IgA and worse Marsh grade in children with T1D-CD.

  • 3

    The optimal anti-TTG IgA cutoff for sparing biopsy in T1D-CD youth is determined to be 11 times the upper limit of normal.

  • 4

    Autoimmunity is more prevalent in T1D-CD individuals, particularly those diagnosed with celiac disease before type 1 diabetes.

  • 5

    Screening for type 1 diabetes in the celiac disease population is recommended due to the higher prevalence of autoimmune comorbidities.

Original Source(s)

Glucometabolic Control and Anti-Transglutaminase Antibodies at Celiac Disease Onset in Type 1 Diabetes Youth

  • by Francesca Di Candia, Francesco Maria Rosanio, Roberto Franceschi, Alessandro Fierro, Riccardo Bonfanti, Francesca Cardella, Valentino Cherubini, Giuseppe D’Annunzio, Barbara Felappi, Dario Iafusco, Brunella Iovane, Claudio Maffeis, Giulio Maltoni, Francesca Olivieri, Gabriele Olivieri, Barbara Piccini, Elvira Piccinno, Barbara Predieri, Ivana Rabbone, Maria Rossella Ricciardi, Giuseppina Salzano, Riccardo Schiaffini, Gianluca Tornese, Angela Zanfardino, Marco Marigliano, Riccardo Troncone, Riccardo Pertile, Luigi Greco, Renata Auricchio, Enza Mozzillo, ISPED Diabetes Study Group Collaborators, Francesco Gallo, Caterina Grosso, Carlo Ripoli, Fiorella De Berardinis, Susanna Coccoli, Valentina Tiberi, Sonia Toni, Maurizio Delvecchio, Rosanna Roppolo, Fortunato Lombardo, Stefano Passanisi, Bruno Bombaci, Alberto Casertano, Nicola Minuto, Marta Bassi, Evelina Maines, Silvia Savastio, Elena Inzaghi, Andrea Rigamonti, Giulio Frontino, Patrizia Bruzzi, Claudia Piona

  • November 4, 2025

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