EUS-guided hepaticogastrostomy versus EUS-guided hepaticogastrostomy with antegrade stent placement in patients with unresectable malignant distal biliary obstruction: a meta-analysis of individual patient data - Takeaways - MDSpire

EUS-guided hepaticogastrostomy versus EUS-guided hepaticogastrostomy with antegrade stent placement in patients with unresectable malignant distal biliary obstruction: a meta-analysis of individual patient data

  • By

  • Mahmoud Shaaban Abdelgalil

  • Ahmad Abdelrazek

  • Mahmoud Samir Mohamed

  • Amro Hassan

  • Manar Alaa Mabrouk

  • Mohamed Nasser

  • Eyad Khalil Alhmeid

  • Abdullah Nizar

  • Abid Wazir

  • Noha Ali

  • Adam Hraybi

  • Ryad iqbal

  • Sadia Paracha

  • Shray Amin

  • July 11, 2026

  • 0 min

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  • 1

    Malignant biliary obstruction (MBO) is primarily caused by pancreatic cancer and poses significant diagnostic and therapeutic challenges.

  • 2

    Endoscopic ultrasound-guided biliary drainage (EUS-BD) is an alternative to ERCP when traditional methods fail due to anatomical difficulties.

  • 3

    Hepaticogastrostomy with antegrade stenting (HGAS) combines two drainage routes, potentially improving outcomes compared to EUS-guided hepaticogastrostomy (HGS) alone.

  • 4

    The study aims to compare the efficacy and safety of EUS-HGS versus EUS-HGAS in patients with unresectable malignant distal biliary obstruction.

  • 5

    Primary outcomes include time to recurrent biliary obstruction (RBO) and need for reintervention, with secondary outcomes assessing technical and clinical success.

Original Source(s)

EUS-guided hepaticogastrostomy versus EUS-guided hepaticogastrostomy with antegrade stent placement in patients with unresectable malignant distal biliary obstruction: a meta-analysis of individual patient data

  • by Mahmoud Shaaban Abdelgalil, Ahmad Abdelrazek, Mahmoud Samir Mohamed, Amro Hassan, Manar Alaa Mabrouk, Mohamed Nasser, Eyad Khalil Alhmeid, Abdullah Nizar, Abid Wazir, Noha Ali, Adam Hraybi, Ryad iqbal, Sadia Paracha, Shray Amin

  • July 11, 2026

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