Serum anti-Müllerian hormone response to pyrroloquinoline quinone supplementation in healthy women: no overall change and exploratory subgroup findings - Takeaways - MDSpire

Serum anti-Müllerian hormone response to pyrroloquinoline quinone supplementation in healthy women: no overall change and exploratory subgroup findings

  • By

  • Saori Tsuji

  • Tsuyoshi Takiuchi

  • Mika Handa

  • Naoki Miura

  • Hisae Aoyagi

  • Yuki Uematsu

  • Miwako Shidomi

  • Kazutake Fukada

  • Chiaki Ogura

  • Tadashi Kimura

  • Michiko Kodama

  • July 10, 2026

  • 0 min

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  • 1

    Pyrroloquinoline quinone (PQQ) supplementation did not significantly change serum anti-Müllerian hormone (AMH) levels in healthy women.

  • 2

    Younger participants with lower baseline AMH showed a non-significant increase in AMH after PQQ supplementation.

  • 3

    Older participants with lower baseline AMH experienced a significant decrease in AMH levels following PQQ supplementation.

  • 4

    The study involved 50 healthy women aged 25–42 years, with blood samples collected before and after 90 days of PQQ supplementation.

  • 5

    Exploratory subgroup analyses indicated inconsistent findings, highlighting the need for larger, placebo-controlled trials.

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