Diagnostic value of combined flow cytometry-based detection of peripheral blood lymphocyte subsets and cytokines for pediatric infectious mononucleosis - Takeaways - MDSpire

Diagnostic value of combined flow cytometry-based detection of peripheral blood lymphocyte subsets and cytokines for pediatric infectious mononucleosis

  • By

  • Kai Tong

  • Xingran Liu

  • Jingxiao Dong

  • Qi Wang

  • Jing Hu

  • Jing Ma

  • June 19, 2026

  • 0 min

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  • 1

    The study evaluated immune function alterations in children with Epstein–Barr virus-associated infectious mononucleosis (IM).

  • 2

    A total of 61 children with IM and 32 healthy controls were enrolled, with significant clinical manifestations observed in the IM group.

  • 3

    Patients with IM exhibited elevated white blood cell counts, lymphocyte counts, and pro-inflammatory cytokines compared to healthy controls.

  • 4

    ROC analysis showed that combined lymphocyte subset and cytokine assessments significantly improved diagnostic accuracy for IM.

  • 5

    The study highlights the potential of flow cytometry and cytokine profiling in enhancing early diagnosis of pediatric infectious mononucleosis.

Original Source(s)

Diagnostic value of combined flow cytometry-based detection of peripheral blood lymphocyte subsets and cytokines for pediatric infectious mononucleosis

  • by Kai Tong, Xingran Liu, Jingxiao Dong, Qi Wang, Jing Hu, Jing Ma

  • June 19, 2026

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