When Guillain-Barré Signals Lyme  - Takeaways - MDSpire

When Guillain-Barré Signals Lyme 

  • March 25, 2026

  • 3 min

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  • 1

    A 61-year-old female patient developed Guillain-Barré syndrome associated with Lyme disease, highlighting diagnostic challenges.

  • 2

    Neurological examination revealed significant lower limb weakness and absent reflexes, consistent with Guillain-Barré syndrome.

  • 3

    Cerebrospinal fluid analysis showed albuminocytologic dissociation, supporting the diagnosis of Guillain-Barré syndrome.

  • 4

    The patient tested positive for Lyme disease, fulfilling CDC criteria, and was treated with intravenous ceftriaxone.

  • 5

    Timely recognition of Lyme disease in atypical Guillain-Barré presentations can significantly improve patient outcomes.

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