The Role of the EASIX Score in Predicting Sinusoidal Obstruction Syndrome and Nonrelapse Mortality in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

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Endothelial injury post-allo-HSCT can lead to complications like sinusoidal obstruction syndrome and increase nonrelapse mortality.
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The EASIX score, derived from routine lab parameters, is proposed to assess endothelial dysfunction and predict HSCT outcomes.
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Previous studies in adults show the EASIX score correlates with various HSCT outcomes, including acute graft-versus-host disease and overall survival.
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This study aims to evaluate the EASIX score's validity in predicting complications and nonrelapse mortality in pediatric allo-HSCT patients.
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The analysis includes data from pediatric patients treated at a single center, focusing on the EASIX score's predictive accuracy for clinical outcomes.

Bone Marrow Transplantation

by Edoardo Muratore, Giacomo Gambuti, Davide Leardini, Francesco Baccelli, Francesco Venturelli, Leyna Larcinese, Francesca Gottardi, Antonia Di Battista, Tamara Belotti, Arcangelo Prete, Riccardo Masetti
December 10, 2024

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