Effectiveness and tolerability of cephalexin and clavulanic acid fixed dose combination, amoxicillin and clavulanic acid fixed dose combination, and azithromycin in patients with pharyngitis in India: a real-world retrospective study from electronic medical records (PHARYSPOR) - Takeaways - MDSpire

Effectiveness and tolerability of cephalexin and clavulanic acid fixed dose combination, amoxicillin and clavulanic acid fixed dose combination, and azithromycin in patients with pharyngitis in India: a real-world retrospective study from electronic medical records (PHARYSPOR)

  • By

  • Subramanyam Sarof

  • Nikita Kariappa Somana

  • Ravindra Channagiri S

  • Ramesh Chinthalapalli Venkataram

  • Jyothi Sharma R

  • Sabhapathi SV

  • Ramakrishnaiah Peddi

  • Sadanandam K

  • Nitin Rai Vohra

  • Lokesh Kumar Bhama

  • Mahendrakumar Shah

  • Vijay Chile

  • Ameeta Gunderia

  • Farad Momin

  • Anit Banerjee

  • Saumitra Kumar

  • Sandeep Rungta

  • Ashik Ikbal

  • Sunil Singhvi

  • Annamalai Natarajan

  • Monjori Mitra

  • Vijay Kadam

  • Shruti Dharmadhikari

  • Chintan Khandhedia

  • Gaurav Puppalwar

  • Neeraj Markandeywar

  • Amey Mane

  • Suyog Mehta

  • July 9, 2026

  • 0 min

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  • 1

    The study assessed the effectiveness of cephalexin-clavulanate compared to co-amoxiclav and azithromycin for treating acute bacterial pharyngitis.

  • 2

    Clinical cure rates by Day 10 were similar across cephalexin-CV, co-amoxiclav, and azithromycin treatment groups.

  • 3

    Cephalexin-CV showed earlier clinical improvement by Day 2 and Day 3 compared to co-amoxiclav and azithromycin.

  • 4

    The requirement for NSAIDs was lower in the cephalexin-CV group compared to the azithromycin group.

  • 5

    Adverse events were minimal across all treatment groups, with mild gastritis reported in the cephalexin-CV group.

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