Assessment of Anterior Scleral Thickness in Acromegaly: A Prospective Multinational Optical Coherence Tomography Study - Takeaways - MDSpire
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Assessment of Anterior Scleral Thickness in Acromegaly: A Prospective Multinational Optical Coherence Tomography Study

  • By

  • Başak Memis

  • Murat Kasikci

  • Gulhan Akbaba

  • Ozgur Erogul

  • February 12, 2026

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  • 1

    Acromegaly is characterized by GH and IGF-1 hypersecretion, leading to tissue hypertrophy and ocular changes.

  • 2

    The study assessed anterior scleral thickness in acromegaly using high-resolution AS-OCT in a prospective, multinational design.

  • 3

    Fifty-five eyes from 28 participants, including 22 acromegaly eyes and 33 controls, were analyzed for scleral thickness.

  • 4

    Scleral thickness measurements were standardized and taken at eight meridians, ensuring accurate assessment.

  • 5

    The study adhered to ethical guidelines and received approval, ensuring informed consent from all participants.

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