The diet-microbiota-inflammation axis and colorectal cancer

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Colorectal cancer (CRC) is a leading cause of cancer morbidity and mortality globally, with increasing incidence in younger populations.
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Dietary patterns significantly influence gut microbiota composition, with high-fiber diets offering protective effects against CRC.
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Dysbiosis and specific microorganisms have been linked to CRC through inflammatory and genotoxic mechanisms.
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Recent advances in sequencing technologies have identified microbial signatures that may serve as diagnostic and prognostic biomarkers for CRC.
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Microbiota-targeted interventions, including probiotics and fecal microbiota transplantation, show promise in CRC prevention and management.

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