Sonazoid-enhanced ultrasound for preoperative localization and characterization of sentinel lymph nodes in patients with cutaneous melanoma - Takeaways - MDSpire
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Ultrasound Enhancement with Sonazoid for Preoperative Identification and Assessment of Sentinel Lymph Nodes in Cutaneous Melanoma Patients

  • By

  • Binbin Jiang

  • Liqi Sun

  • Lu Si

  • Jiayong Liu

  • Chuanliang Cui

  • Kun Yan

  • Shanshan Yin

  • May 25, 2026

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  • 1

    Cutaneous malignant melanoma is a prevalent skin cancer, with sentinel lymph nodes being critical for staging and treatment planning.

  • 2

    Sentinel lymph node biopsy is the standard procedure for clinically node-negative melanoma patients, providing essential prognostic information.

  • 3

    Traditional SLN localization methods, like lymphoscintigraphy, have limitations including allergic reactions and radiation risks.

  • 4

    Sonazoid, a novel ultrasound contrast agent, enhances SLN visualization and offers advantages over traditional tracers in melanoma staging.

  • 5

    This study evaluates the feasibility and safety of Sonazoid for SLN identification, aiming to improve preoperative staging in melanoma patients.

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