Submucosal uterine leiomyoma with complete cystic degeneration mimicking an empty gestational sac: a case report and literature review - Takeaways - MDSpire

Submucosal uterine leiomyoma with complete cystic degeneration mimicking an empty gestational sac: a case report and literature review

  • By

  • Shunlin Lin

  • Di An

  • Zihua Xu

  • June 26, 2026

  • 0 min

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  • 1

    Uterine leiomyomas are the most common benign pelvic tumors in women, with cystic degeneration being a rare variant.

  • 2

    A 42-year-old woman presented with irregular vaginal bleeding and abdominal pain, leading to the discovery of a large cystic lesion.

  • 3

    Initial imaging suggested an empty gestational sac, but negative serum β-hCG results prompted further evaluation.

  • 4

    Hysteroscopy revealed a giant cystic tumor, which was excised and diagnosed as a completely degenerated submucosal leiomyoma.

  • 5

    Immunohistochemistry confirmed the diagnosis, highlighting the importance of histopathological examination in atypical cases.

Original Source(s)

Submucosal uterine leiomyoma with complete cystic degeneration mimicking an empty gestational sac: a case report and literature review

  • by Shunlin Lin, Di An, Zihua Xu

  • June 26, 2026

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