Case Report: Duodenal Neoplasm-induced Panniculitis - Takeaways - MDSpire

Case Report: Duodenal Neoplasm-induced Panniculitis

  • By

  • Mao, Hanxiao

  • Zeng, Ziyuan

  • Xie, Lvsha

  • He, Yuanmin

  • May 4, 2026

  • 0 min

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  • 1

    Panniculitis is an inflammatory disorder of subcutaneous adipose tissue and can be a paraneoplastic syndrome.

  • 2

    The case involved a 79-year-old male with painful erythematous nodules on his lower limbs and no gastrointestinal symptoms.

  • 3

    Histopathological evaluation revealed fat necrosis, calcification, and ghost cells in the skin.

  • 4

    Laboratory tests showed significantly elevated serum lipase levels, and imaging identified a duodenal mass with liver metastases.

  • 5

    The case highlights the importance of recognizing panniculitis as a potential indicator of underlying duodenal tumors.

Original Source(s)

Case Report: Duodenal Neoplasm-induced Panniculitis

  • by Mao, Hanxiao , Zeng, Ziyuan , Xie, Lvsha , He, Yuanmin

  • May 4, 2026

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