Reference values and Z-scores for left ventricular global longitudinal strain in healthy Colombian children: an echocardiographic study - Takeaways - MDSpire

Reference values and Z-scores for left ventricular global longitudinal strain in healthy Colombian children: an echocardiographic study

  • By

  • Yudisay Molina-Mora

  • Andrés Felipe Rubio-Duarte

  • Yuli Salcedo-Oyola

  • Alicia Rincón-Rangel

  • Claudia C. Colmenares-Mejía

  • Valeria Ramirez-Jaramillo

  • Claudia Ximena Flórez-Rodríguez

  • June 5, 2026

  • 0 min

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  • 1

    This study established left ventricular global longitudinal strain (GLS) reference values for healthy Colombian children aged 2 to 17 years.

  • 2

    GLS varied significantly with age, showing more negative values in younger children and progressively less negative values in adolescents.

  • 3

    A moderate correlation was found between GLS and age (r = 0.49; p < 0.001), while GLS had a weak correlation with left ventricular ejection fraction.

  • 4

    The study highlights the importance of using population-specific reference values for GLS to accurately assess myocardial function in children.

  • 5

    Findings emphasize the need to consider age when interpreting GLS measurements, as traditional volumetric measures may not reflect myocardial deformation.

Original Source(s)

Reference values and Z-scores for left ventricular global longitudinal strain in healthy Colombian children: an echocardiographic study

  • by Yudisay Molina-Mora, Andrés Felipe Rubio-Duarte, Yuli Salcedo-Oyola, Alicia Rincón-Rangel, Claudia C. Colmenares-Mejía, Valeria Ramirez-Jaramillo, Claudia Ximena Flórez-Rodríguez

  • June 5, 2026

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