Pancreatic arteriovenous malformations as a manifestation of hereditary haemorrhagic telangiectasia (Rendu-Osler-Weber disease): a systematic review - Takeaways - MDSpire
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Pancreatic Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia: A Comprehensive Review of Existing Cases

  • By

  • Isabel de Jager

  • Ebba Asplund

  • Nikolaos Kartalis

  • Poya Ghorbani

  • Nina Bloch

  • Johannes Matthias Löhr

  • Miroslav Vujasinovic

  • September 25, 2026

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  • 1

    This systematic review identified 19 patients with pancreatic arteriovenous malformations (AVMs) associated with hereditary hemorrhagic telangiectasia (HHT).

  • 2

    Females represented 58% of the patients, with a mean age of 52 years; 50% were asymptomatic and 73% showed no laboratory abnormalities.

  • 3

    CT was the primary diagnostic method used in 56% of cases, and the mean size of pancreatic AVMs was reported as 7.1 mm.

  • 4

    Conservative management was the predominant treatment approach, utilized in 69% of the cases reviewed.

  • 5

    The study concluded that pancreatic AVMs in HHT are generally smaller and less symptomatic compared to those in the general population.

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