Evaluating the connection between cardiometabolic disorders and the likelihood of aggressive prostate cancer: a systematic review and meta-analysis - Takeaways - MDSpire

Evaluating the connection between cardiometabolic disorders and the likelihood of aggressive prostate cancer: a systematic review and meta-analysis

  • By

  • Aurmin J. Amirmokri

  • Christopher A. Loffredo

  • Kepher H. Makambi

  • Nancy A. Dawson

  • October 25, 2025

  • 0 min

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  • 1

    Prostate cancer is the most common malignancy among men in the U.S., with an increasing incidence rate of 3% annually since 2014.

  • 2

    Cardiometabolic diseases, including obesity and type 2 diabetes, are prevalent in the U.S. and may increase the risk of aggressive prostate cancer.

  • 3

    Health disparities exist in prostate cancer incidence and mortality, particularly affecting Black Americans who face higher rates of obesity.

  • 4

    This systematic review aims to explore the relationship between cardiometabolic disorders and aggressive prostate cancer to improve patient outcomes.

  • 5

    The study adheres to PRISMA guidelines and includes peer-reviewed longitudinal cohort studies published after 2015.

Original Source(s)

Evaluating the connection between cardiometabolic disorders and the likelihood of aggressive prostate cancer: a systematic review and meta-analysis

  • by Aurmin J. Amirmokri, Christopher A. Loffredo, Kepher H. Makambi, Nancy A. Dawson

  • October 25, 2025

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