Risk association and diagnostic value of body roundness index for cardiovascular-kidney-metabolic-related outcomes: a systematic review and meta-analysis - Takeaways - MDSpire

Risk association and diagnostic value of body roundness index for cardiovascular-kidney-metabolic-related outcomes: a systematic review and meta-analysis

  • By

  • Hongjia Fu

  • Hui Liu

  • Yamei Han

  • Tie Wang

  • Jia Yu

  • Wei Liu

  • Zhen Liu

  • Xiuru Hu

  • Zhenyan Shen

  • Yunxia Gao

  • April 14, 2026

  • 0 min

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  • 1

    The Body Roundness Index (BRI) is a novel measure for assessing visceral fat and its association with Cardiovascular-Kidney-Metabolic (CKM) outcomes.

  • 2

    A systematic review included 93 studies, indicating BRI's significant association with multiple CKM-related outcomes, varying by outcome and gender.

  • 3

    BRI demonstrated good discriminatory ability for metabolic syndrome, while its predictive ability for chronic kidney disease and cardiovascular disease was limited.

  • 4

    BRI serves as a complementary tool to traditional anthropometric indices, enhancing risk identification and stratification for CKM-related risks.

  • 5

    Further high-quality prospective cohort studies are needed to define the long-term predictive value and clinical utility of BRI across diverse populations.

Original Source(s)

Risk association and diagnostic value of body roundness index for cardiovascular-kidney-metabolic-related outcomes: a systematic review and meta-analysis

  • by Hongjia Fu, Hui Liu, Yamei Han, Tie Wang, Jia Yu, Wei Liu, Zhen Liu, Xiuru Hu, Zhenyan Shen, Yunxia Gao

  • April 14, 2026

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