Transcriptomic profiling and IgM and IgT repertoire dynamics in rainbow trout gills following primary and secondary challenge with Lactococcus petauri - Takeaways - MDSpire

Transcriptomic profiling and IgM and IgT repertoire dynamics in rainbow trout gills following primary and secondary challenge with Lactococcus petauri

  • By

  • Aitor Arrogante

  • Esther Morel

  • Beatriz Abós

  • Samuel Vicente-Gil

  • Pablo Jiménez-Barrios

  • Patricia Díaz-Rosales

  • Pedro Perdiguero

  • J. Germán Herranz-Jusdado

  • Carolina Tafalla

  • June 16, 2026

  • 0 min

Share

  • 1

    Rainbow trout gills contain gill-associated lymphoid tissue, composed of scattered B and T cells, and organized interbranchial lymphoid tissue.

  • 2

    The study investigated immune responses in rainbow trout gills after exposure to Lactococcus petauri, focusing on memory responses.

  • 3

    Re-infected rainbow trout showed modified gene expression related to adaptive immunity and significant clonal expansion of IgM and IgT.

  • 4

    Increased levels of specific IgM were produced by re-infected fish both locally in gills and in serum, without apparent clonal selection.

  • 5

    Findings suggest that gills play a role in localized adaptive immune regulation during secondary immune responses in teleost fish.

Original Source(s)

Transcriptomic profiling and IgM and IgT repertoire dynamics in rainbow trout gills following primary and secondary challenge with Lactococcus petauri

  • by Aitor Arrogante, Esther Morel, Beatriz Abós, Samuel Vicente-Gil, Pablo Jiménez-Barrios, Patricia Díaz-Rosales, Pedro Perdiguero, J. Germán Herranz-Jusdado, Carolina Tafalla

  • June 16, 2026

Related Content

Hypogammaglobulinaemia in patients with ANCA-associated vasculitis treated with rituximab

Hospital-acquired infections in preterm infants with gestational age <32 weeks: a retrospective study of clinical characteristics, pathogen distribution, and associated factors

Long-Acting Injectable Antiretroviral Therapy in Medicare-Enrolled Adults With HIV