Case Report and Epidemiological Investigation of Healthcare-associated Plasmodium falciparum Malaria Transmission in Westchester County, New York—2023

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A 65-year-old Westchester County resident was diagnosed with Plasmodium falciparum malaria on October 2, 2023, without recent international travel.
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Epidemiological investigation revealed potential exposure routes, including domestic travel and hospitalizations overlapping with malaria cases.
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Genetic analysis indicated blood-borne transmission in a healthcare setting from a concurrently hospitalized traveler with confirmed malaria.
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No mosquito-transmitted cases were identified in New York, and no additional healthcare-associated cases were reported following the investigation.
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The investigation underscores the importance of identifying locally acquired malaria infections to prevent further transmission.

Open Forum Infectious Diseases

by Jennifer L White, Karen Southwick, Susan Madison-Antenucci, Nicholas P Piedmonte, Sujoy Gayen, Brooke Clemons, Monica Quinn, Kelly Barrett, P Bryon Backenson, Mike Antwi, Sally Slavinski, Ellen Lee, Ada Huang, Kevin Smith, Elissa Guzzardi, Jennifer C Hunter, Kimberly L McKinney, Kimberly E Mace, Alison D Ridpath, Seymour Williams, Joel L N Barratt, David Jacobson, Edwin Pierre-Louis, Marko Bajic, Julia Kelley, Peter D McElroy, Brian H Raphael, Alan Bulbin
December 10, 2025

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