SAPHO syndrome with membranous nephropathy and analgesic-induced nephropathy: a case report - Takeaways - MDSpire

SAPHO syndrome with membranous nephropathy and analgesic-induced nephropathy: a case report

  • By

  • Yuxin Qiao

  • Zuo Wang

  • Guohua Li

  • Duo Zhang

  • June 2, 2026

  • 0 min

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  • 1

    SAPHO syndrome is a rare autoimmune disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis.

  • 2

    The case study reports a 43-year-old male with SAPHO syndrome who developed stage II membranous nephropathy and analgesic nephropathy.

  • 3

    The patient presented with joint pain, skin pustules, proteinuria, and elevated serum creatinine, indicating renal involvement.

  • 4

    Treatment included intravenous antibiotics and corticosteroids, leading to symptom resolution and improved renal function.

  • 5

    At one-year follow-up, the patient achieved nearly complete remission of proteinuria and stable renal function.

Original Source(s)

SAPHO syndrome with membranous nephropathy and analgesic-induced nephropathy: a case report

  • by Yuxin Qiao, Zuo Wang, Guohua Li, Duo Zhang

  • June 2, 2026

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