Clinical Characteristics and Epidemiological Patterns of Early-Onset Colorectal Cancer in Young Adults and Middle-Aged Individuals: Insights from SEER 17 and GBD 2021 Data Over the Last 15 Years - Takeaways - MDSpire

Clinical Characteristics and Epidemiological Patterns of Early-Onset Colorectal Cancer in Young Adults and Middle-Aged Individuals: Insights from SEER 17 and GBD 2021 Data Over the Last 15 Years

  • By

  • Xuanhong Jin

  • Bingjun Bai

  • Yang Pan

  • Shangzhi Xie

  • Yao Chen

  • Kaibo Ding

  • Fei Wu

  • Xing Gao

  • Liangkun You

  • Hongming Pan

  • Binbin Xie

  • November 22, 2025

  • 0 min

Share

  • 1

    Early-onset colorectal cancer (EOCRC) is increasingly diagnosed in individuals under 50, presenting at advanced stages with distinct features.

  • 2

    Research indicates that EOCRC patients, especially those aged 20-29, may have more aggressive disease phenotypes compared to older age groups.

  • 3

    The study utilized SEER 17 and GBD 2021 data to analyze clinical characteristics and epidemiological trends of EOCRC over the past 15 years.

  • 4

    VEOCRC is defined as colorectal cancer in patients aged 15-29, while MAEOCRC includes those aged 30-49, highlighting significant age-related differences.

  • 5

    Using ICD-10 classification, the study aims to provide clearer insights into EOCRC trends by excluding carcinoid tumors from analysis.

Original Source(s)

Clinical Characteristics and Epidemiological Patterns of Early-Onset Colorectal Cancer in Young Adults and Middle-Aged Individuals: Insights from SEER 17 and GBD 2021 Data Over the Last 15 Years

  • by Xuanhong Jin, Bingjun Bai, Yang Pan, Shangzhi Xie, Yao Chen, Kaibo Ding, Fei Wu, Xing Gao, Liangkun You, Hongming Pan, Binbin Xie

  • November 22, 2025

Related Content

Editorial: Insights into gastrointestinal cancer metastasis from preclinical models

Exploring the molecular mechanism of Coptis-cinnamon in combating gastric cancer via the MAPK Pathway based on network pharmacology

Pancreatic Cancer Risk in Patients With Low-Risk Cystic Lesions