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1
Micronodular perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal neoplasm of the appendix, recently reclassified within the PEComa family.
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2
A 23-year-old man with recurrent abdominal pain underwent laparoscopic appendectomy, revealing multiple micronodular nests of epithelioid cells.
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3
Histological examination showed abundant eosinophilic granular cytoplasm and small nuclei, with immunohistochemical positivity for SMA, Desmin, and HMB-45.
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4
The Ki-67 proliferation index was less than 1%, indicating low mitotic activity and supporting the diagnosis of micronodular PEComa.
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5
At 8 months post-surgery, the patient reported significant improvement in symptoms, with no clinical evidence of recurrence.
