Comparative analysis of indocyanine green and technetium-99m for sentinel lymph node localization in breast cancer – institutional experience - Takeaways - MDSpire

Comparative analysis of indocyanine green and technetium-99m for sentinel lymph node localization in breast cancer – institutional experience

  • By

  • Csaba Kósa

  • Hajnalka Kulcsár

  • Klaudia Balog

  • Tamás Dinya

  • Lóránt Illésy

  • Gergő Kincses

  • Tamás Kuna

  • Péter Juhász

  • Dezső Tóth

  • May 7, 2026

  • 0 min

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  • 1

    Indocyanine green (ICG) fluorescence imaging is a radiation-free alternative for sentinel lymph node biopsy (SLNB) in breast cancer.

  • 2

    The study included 106 patients, comparing ICG with technetium-99m (Tc-99m) for sentinel lymph node detection.

  • 3

    ICG achieved a sentinel node detection rate of 90.6%, while Tc-99m had a rate of 97.1%, indicating comparable effectiveness.

  • 4

    No ICG-related complications or adverse events were reported, supporting its safety in clinical practice.

  • 5

    The findings suggest ICG's integration into standard breast cancer surgery protocols, pending further multicenter validation.

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